Common Crohn's disease-predisposing variants of the CARD15/NOD2 gene are not associated with Behcet's disease in Turkey

Uyar F. A., Saruhan-Direskeneli G., Gul A.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.22, sa.4, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 4
  • Basım Tarihi: 2004
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Behcet's disease, Crohn's disease, CARD15, NOD2, genetic susceptibility, NOD2, SUSCEPTIBILITY, MUTATIONS, DIAGNOSIS, ARTHRITIS, SYNDROME/, CRITERIA, LOCUS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective. There are many extra-intestinal findings of Crohn's disease (CD), such as oral and genital ulcers, erythema nodosum, uveitis and arthritis, resembling the manifestations of Behcet's disease (BD). It is also very difficult to distinguish the gastrointestinal involvement of BD from that of CD in some patients. Hence, this study aimed to investigate a possible involvement of the common CD-predisposing CARD15 variants in the genetic susceptibility to BD.