Identification of microRNA profile specific to cancer stem-like cells directly isolated from human larynx cancer specimens

Karatas O. F., Suer İ., Yuceturk B., Yilmaz M., Oz B., Guven G., ...Daha Fazla

BMC CANCER, cilt.16, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1186/s12885-016-2863-3
  • Dergi Adı: BMC CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Cancer stem-like cells, MicroRNAs, Larynx cancer, CD133, microRNA-signature, EPITHELIAL-MESENCHYMAL TRANSITION, TUMOR-INITIATING CELLS, COUPLED RECEPTOR GPR49, EXPRESSION SIGNATURE, PROSTATE-CANCER, SMALL-INTESTINE, MIR-200 FAMILY, SELF-RENEWAL, E-CADHERIN, CARCINOMA
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Emerging evidences proposed that microRNAs are associated with regulation of distinct physiopathological processes including development of normal stem cells and carcinogenesis. In this study we aimed to investigate microRNA profile of cancer stem-like cells (CSLCs) isolated form freshly resected larynx cancer (LCa) tissue samples.