Durmuş Tekçe H., Yeşilot N., Tuncay R., Çoban O., Zarkobahar S.

21.European Stroke Conference, Lisbon, Portugal, 22 - 24 May 2012, pp.651-652

  • Publication Type: Conference Paper / Summary Text
  • City: Lisbon
  • Country: Portugal
  • Page Numbers: pp.651-652
  • Istanbul University Affiliated: Yes


BACKROUND: Stroke survivors are at

high risk of recurrent stroke, communitybased

studies show that this risk is about

30%. Recurrent strokes tend to be more

deadly than the first stroke and lead to

further neurological impairment. In this

sudy, in-hospital stroke recurrence in

a university hospital stroke unit setting

were investigated.


registry data of 2128 patients hospitalized

at the Istanbul Faculty of Medicine,

Department of Neurology, Edip Aktin

Stroke Unit between 1994-2007 were

evaluated. Recurent stroke was defined

as a new neurological deficit not caused

by neurological complications such as

edema, mass effect or hemorrhagic transformation

or progression of the index

event. Clinical, laboratory and neuroimaging

findings of 67 recurrent ischemic

stroke patients were compared with ischemic

stroke patients (n = 1658) without

any recurrence. Statistical methods used

were; chi-squared test for parametric

variables, t-test for continuous variables

and univariate and multivariate analysis

using SPSS version 15.0.

RESULTS: In- hospital stroke reccurence

rate was 3.9% (n = 83/2128) in

all stroke patients and %4 in ischemic

stroke (IS) patients. There were no statistically

significant differences between

IS patients with and without recurrence

in terms of demographic features, and

most traditional risk factors. Only peripheral

vascular disease frequency was significantly higher in the recurrent stroke group (p = 0.05, 95% CI = 0.98 to

5.524). Posterior circulation syndrome

(POCS) and was significantly more frequently

encountered in the recurrent

stroke group (p = 0.012).The most important

factor in determining the recurrence

of IS was large artery atherosclerosis

(LAS) (p <0.001, 95% CI = 0.062 to


CONCLUSION: In a stroke unit where

acute stroke treatments were mostly unavailable,

a higher in-hospital stroke recurrence

rate associated with LAS in IS

patients may be indicative of the importance

of early theraputic intervention.