Correlation between H-1 MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis


HANOGLU L., OZKARA C. , KESKINKILIC C., ALTIN U., Uzan M. , TUZGEN S. , ...More

EPILEPSIA, vol.45, no.6, pp.632-640, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1111/j.0013-9580.2004.54302.x
  • Title of Journal : EPILEPSIA
  • Page Numbers: pp.632-640

Abstract

Purpose: Proton magnetic resonance spectroscopy (H-1 MRS). which can demonstrate neuronal loss and gliosis, may be used as a sensitive tool for lateralization of temporal lobe epilepsy (TLE). Although the correlation between the memory functions and H-1 MRS has been investigated, its predictive value after surgery has not been studied previously. This Study evaluated memory and H-1 MRS values of medically intractable patients with mesial TLE and hippocampal sclerosis (MTLE-HS) before and after selective amygdalohippocampectomy (SAH).