Neuroleptic Malignant Syndrome Due to Risperidone Treatment in a Child With Joubert Syndrome


Vurucu S., Congologlu A., ALTUN BİNGÖL D., Unay B., Akin R.

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.101, sa.3, ss.273-275, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 101 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/s0027-9684(15)30858-0
  • Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.273-275
  • Anahtar Kelimeler: central nervous system disorders, neurology, drugs, RISK-FACTORS
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Joubert syndrome is a rare autosomal recessive disease characterized by hypotonia, ataxia, episodic hyperpnea, psychomotor retardation, abnormal ocular movements, cerebellar vermian hypoplasia, and molar tooth sign on magnetic resonance imaging. Neuroleptic malignant syndrome is an uncommon and potentially fatal idiosynchratic reaction of antipsychotic drugs, in which the clinical scenario encompass muscular rigidity, hyperthermia, autonomic dysfunction, altered consciousness, high creatinine phosphokinase levels, and leukocytosis. This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome.