The Effect of ZAP-70 Expression on Disease Progression in Early-Stage (Binet A) B-CLL Patients


URE U., Ar M. C. , Baslar Z., Soysal T., Ongoren S., Gulseven M., ...More

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, vol.26, no.4, pp.317-321, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2009
  • Journal Name: TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.317-321
  • Istanbul University Affiliated: Yes

Abstract

Objectives: Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with various clinical findings. Prognostic markers predicting the clinical outcome in early-stage CLL would play a major role in disease management. Various studies have shown that zeta-associated protein 70 (ZAP-70) provides significant prognostic information This retrospective, single-centre study evaluates the effect of ZAP-70 on disease progression in early-stage B-CLL