The Effects of Colchicum baytopiorum on Regulatory Genes of Apoptotic and Autophagic Cell Death in HeLa Cells

Ozsoylemez, Ozlem; Ozturk, Melek; Sutlupinar, Nurhayat; Kayacan, Sera; Tuncdemir, Matem; Ozcan, FATMA

doi:10.2174/1389201018666161109113543

The Effects of Colchicum baytopiorum on Regulatory Genes of Apoptotic and Autophagic Cell Death in HeLa Cells

Ozsoylemez O. D., Ozturk M., Sutlupinar N., Kayacan S., Tuncdemir M., Ozcan G.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, cilt.17, sa.15, ss.1369-1376, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 17 Sayı: 15
Basım Tarihi: 2016
Doi Numarası: 10.2174/1389201018666161109113543
Dergi Adı: CURRENT PHARMACEUTICAL BIOTECHNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1369-1376
İstanbul Üniversitesi Adresli: Evet

Özet

Background: The natural products have increasing important for the development of anticancer agents. Colchicum baytopiorum C.D. Brickell (C. baytopiorum), an endemic species for Turkey, contains colchicine and its derivatives. Stimulation of apoptotic and autophagy-mediated cell deaths are effective strategy for anticancer therapies.