The Effects of Colchicum baytopiorum on Regulatory Genes of Apoptotic and Autophagic Cell Death in HeLa Cells


Ozsoylemez O. D. , Ozturk M., Sutlupinar N., Kayacan S., Tuncdemir M., Ozcan G.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, vol.17, no.15, pp.1369-1376, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 15
  • Publication Date: 2016
  • Doi Number: 10.2174/1389201018666161109113543
  • Title of Journal : CURRENT PHARMACEUTICAL BIOTECHNOLOGY
  • Page Numbers: pp.1369-1376

Abstract

Background: The natural products have increasing important for the development of anticancer agents. Colchicum baytopiorum C.D. Brickell (C. baytopiorum), an endemic species for Turkey, contains colchicine and its derivatives. Stimulation of apoptotic and autophagy-mediated cell deaths are effective strategy for anticancer therapies.