Bladder Wall Telangiectasia in a Patient with Ataxia-Telangiectasia and How to Manage?


Aygun F. D. , Nepesov S., Cokugras H., Camcioglu Y.

CASE REPORTS IN PEDIATRICS, 2015 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/615368
  • Journal Name: CASE REPORTS IN PEDIATRICS
  • Journal Indexes: Emerging Sources Citation Index

Abstract

Ataxia-telangiectasia (A-T) is a rare neurodegenerative, inherited disease causing severe morbidity. Oculocutaneous telangiectasias are almost constant findings among the affected cases as telangiectasia is considered the main clinical finding for diagnosis. Vascular abnormalities in organs have been reported infrequently but bladder wall telangiectasias are extremely rare. We aimed to report recurrent hemorrhage from bladder wall telangiectasia in a 9-year-old boy with A-T who had received intravenous cyclophosphamide for non-Hodgkin's lymphoma. Since A-T patients are known to be more susceptible to chemical agents, we suggested that possibly cyclophosphamide was the drug which induced bladder wall injury in this patient.