Complicated Appendicitis: Are Extended Antibiotics Necessary? A Post Hoc Analysis of the EAST Appendicitis "MUSTANG" Study

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Eddine S. B. Z., Dodgion C. M., Qian S., Trevino C., De Moya M. A., Yeh D. D.

JOURNAL OF SURGICAL RESEARCH, vol.247, pp.508-513, 2020 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 247
• Publication Date: 2020
• Doi Number: 10.1016/j.jss.2019.09.054
• Journal Name: JOURNAL OF SURGICAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
• Page Numbers: pp.508-513
• Keywords: Appendicitis, Complicated appendicitis, Antibiotics, APPENDECTOMY, MULTICENTER, DURATION, TRIAL
• Istanbul University Affiliated: No

Abstract

Background: The need for extended postoperative antibiotics (Abx) for complicated (gangrenous or perforated) appendicitis (CA) remains unclear. We hypothesize that giving <= 24 h of Abx for CA is not inferior to a longer duration in preventing infectious complications after appendectomy.