Comparison of clinical, laboratory and radiological features in confirmed and unconfirmed COVID-19 patients

Surme S., Tuncer G., Copur B., Zerdali E., Nakir I. Y., Yazla M., ...Daha Fazla

FUTURE MICROBIOLOGY, cilt.16, sa.18, ss.1389-1400, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 18
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2217/fmb-2021-0162
  • Dergi Adı: FUTURE MICROBIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1389-1400
  • Anahtar Kelimeler: close contact, complete blood count, COVID-19, diagnosis, platelet, SARS-CoV-2 PCR, COMMUNITY-ACQUIRED PNEUMONIA, PERFORMANCE, TESTS
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Background: We aimed to compare the clinical, laboratory and radiological findings of confirmed COVID-19 and unconfirmed patients. Methods: This was a single-center, retrospective study. Results: Overall, 620 patients (338 confirmed COVID-19 and 282 unconfirmed) were included. Confirmed COVID-19 patients had higher percentages of close contact with a confirmed or probable case. In univariate analysis, the presence of myalgia and dyspnea, decreased leukocyte, neutrophil and platelet counts were best predictors for SARS-CoV-2 RT-PCR positivity. Multivariate analyses revealed that only platelet count was an independent predictor for SARS-CoV-2 RT-PCR positivity. Conclusion: Routine complete blood count may be helpful for distinguishing COVID-19 from other respiratory illnesses at an early stage, while PCR testing is unique for the diagnosis of COVID-19.