Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies

Brand, Judith; Rovers, Maroeska; Yeap, Bu; Schneider, Harald; Tuomainen, Tomi-Pekka; Haring, Robin; Corona, Giovanni; Onat, Altan; Maggio, Marcello; Bouchard, Claude; Tong, Peter; Chen, Richard; Akishita, Masahiro; Gietema, Jourik; Gannage-Yared, Marie-Helene; Unden, Anna-Lena; Hautanen, Aarno; Goncharov, Nicolai; Kumanov, Philip; Chubb, S.; Almeida, Osvaldo; Wittchen, Hans-Ulrich; Klotsche, Jens; Wallaschofski, Henri; Voelzke, Henry; Kauhanen, Jussi; Salonen, Jukka; Ferrucci, Luigi; van der Schouw, Yvonne

doi:10.1371/journal.pone.0100409

Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies

Brand J. S., Rovers M. M., Yeap B. B., Schneider H. J., Tuomainen T., Haring R., ...More

PLOS ONE, vol.9, no.7, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 9 Issue: 7
Publication Date: 2014
Doi Number: 10.1371/journal.pone.0100409
Journal Name: PLOS ONE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Istanbul University Affiliated: Yes

Abstract

Background: Low total testosterone (TT) and sex hormone-binding globulin (SHBG) concentrations have been associated with the metabolic syndrome (MetS) in men, but the reported strength of association varies considerably.