The Relationship of White Matter Hyperintensities with Depressive Symptoms and Daily Living Activities in Early-Stage Alzheimer's Disease Patients

Bilgic, Başar; Bayram, Ali; Hanagasi, Haşmet; Tumac, Ayfer; Uysal, Pinar; Senturk, Gulben; Alpsan, Hale; Lohmann, Ebba; Gurvit, İbrahim; Emre, Murat

doi:10.4274/npa.y6603

The Relationship of White Matter Hyperintensities with Depressive Symptoms and Daily Living Activities in Early-Stage Alzheimer's Disease Patients

Atıf İçin Kopyala

Bilgic B., Bayram A., Hanagasi H. A., Tumac A., Uysal P., Senturk G., ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.50, sa.4, ss.360-363, 2013 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 50 Sayı: 4
Basım Tarihi: 2013
Doi Numarası: 10.4274/npa.y6603
Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.360-363
İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Cerebral white matter hyperintensities (WMHs) detected on magnetic resonance imaging scans are frequently seen in both Alzheimer's disease (AD) and depression patients and believed to play an important role in cognition and mood. Depressive symptoms and depression may accompany AD in all stages of the disease. The aim of the study was to evaluate the relationship of regional WMHs with depressive symptoms, cognitive status, medial temporal lobe atrophy, and daily living activities in early-stage AD patients.