The effects of airway pressure and inspiratory time on bacterial translocation

Ozcan P., Cakar N., Tugrul S., Akinci O., Cagatay A., Yilmazbayhan D., ...More

ANESTHESIA AND ANALGESIA, vol.104, no.2, pp.391-396, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1213/01.ane.0000253486.90587.a8
  • Journal Name: ANESTHESIA AND ANALGESIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.391-396
  • Istanbul University Affiliated: Yes

Abstract

BACKGROUND: Mechanical ventilation with high peak inspiratory pressure (PIP) induces lung injury and bacterial translocation from the lung into the systemic circulation. We investigated the effects of increased inspiratory time on translocation of intratracheally inoculated bacteria during mechanical ventilation with and without extrinsic positive end-expiratory pressure (PEEP).