Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study

Genc A., Gedik B., ERDEM M. A., ÇANKAYA A. B.

International Journal of Medical Sciences, vol.22, no.14, pp.3617-3624, 2025 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 14
  • Publication Date: 2025
  • Doi Number: 10.7150/ijms.113282
  • Journal Name: International Journal of Medical Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.3617-3624
  • Keywords: clinical outcomes, dental autotransplantation, oral surgery, platelet-rich plasma, root development
  • Istanbul University Affiliated: Yes

Abstract

Background: Dental autotransplantation, the surgical relocation of a tooth within the same individual, offers a valuable alternative to implants for preserving alveolar bone integrity and achieving functional restoration. This study aimed to assess the short-term impact of platelet-rich plasma (PRP) on clinical outcomes in autotransplanted teeth with fully and partially developed roots. Methods: A total of 20 patients, aged 18-25, were randomly assigned to either a PRP or non-PRP group, with subgroups based on root development stage. Key outcomes—including tooth vitality, periodontal probing depth, mobility, pain, and root resorption—were evaluated at 1 week, 1, 3, 6, and 12 months post-transplant. Results: Findings indicated no statistically significant differences between PRP-treated and control groups across all outcomes, suggesting limited PRP efficacy in enhancing short-term outcomes in mature teeth with developed roots. Conclusions: These results underscore the importance of root maturity and atraumatic surgical technique in autotransplantation success, while highlighting that PRP may not significantly affect outcomes in teeth with completed root development.