Tumour Necrosis Factor-alpha and Nuclear Factor-kappa B Gene Variants in Sepsis
BALKAN MEDICAL JOURNAL, cilt.35, sa.1, ss.30-35, 2018 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 1
- Basım Tarihi: 2018
- Doi Numarası: 10.4274/balkanmedj.2017.0246
- Dergi Adı: BALKAN MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.30-35
- Anahtar Kelimeler: Sepsis, polymorphism, tumor necrosis factor-alpha, NF-kappa B, NFKB1 PROMOTER POLYMORPHISM, INTERLEUKIN-6 PLASMA-LEVELS, TNF-ALPHA, SEPTIC SHOCK, ASSOCIATION, MORTALITY, SUSCEPTIBILITY, NF-KAPPA-B1, CYTOKINES, CHILDREN
- İstanbul Üniversitesi Adresli: Evet
Özet
Background: The humoral system is activated and various cytokines are released due to infections in tissues and traumatic damage. Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial proteins of inflammation such as tumour necrosis factor-alpha.