Smaller Gray Matter Volumes in Frontal and Parietal Cortices of Solvent Abusers Correlate with Cognitive Deficits

Aydin K., KIRCAN S., Sarwar S., Okur O., Balaban E.

AMERICAN JOURNAL OF NEURORADIOLOGY, cilt.30, sa.10, ss.1922-1928, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 10
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3174/ajnr.a1728
  • Dergi Adı: AMERICAN JOURNAL OF NEURORADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1922-1928
  • İstanbul Üniversitesi Adresli: Evet

Özet

BACKGROUND AND PURPOSE: Abuse of toluene-containing organic solvents by inhalation is a prevalent practice among adolescents. Long-term abuse of toluene causes cognitive deficits. The mechanism of cognitive deficits induced by long-term toluene abuse has not yet been defined. In the current study, we assessed the effects of chronic toluene abuse on cortical gray matter volume and the association between cognitive impairment and cortical gray matter volume distribution in chronic toluene abusers.