Copy For Citation
BATU OTO B., AYKUT V., Gunes M., Korkmaz R., Isman F. K., AĞIRBAŞLI M. A.
EXPERIMENTAL EYE RESEARCH, vol.215, 2022 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
215
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Publication Date:
2022
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Doi Number:
10.1016/j.exer.2022.108921
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Journal Name:
EXPERIMENTAL EYE RESEARCH
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
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Keywords:
Diabetic retinopathy, sLRP-1, Biomarker, Serum lipids, Serum LRP-1, APOLIPOPROTEIN-E, ALPHA(2)-MACROGLOBULIN, BIOMARKER, LRP1, BETA, SLRP1, EYES
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Istanbul University Affiliated:
No
Abstract
Low-density lipoprotein receptor-related protein-1 (LRP-1) is a large transmembrane receptor. LRP-1 plays a role in diverse cellular processes, including lipid metabolism, cell growth, migration, and regeneration. Soluble form of LRP-1 (sLRP-1) can be detected in serum. sLRP-1 can serve as a biomarker of atherosclerosis and cardiometabolic diseases. This study investigated the concentrations of the circulating serum sLRP-1 in patients with retinopathy and type 2 diabetes mellitus.