Prenatal thrombosis of renal veins and the inferior vena cava in a newborn with double heterozygosity for the factor V Leiden and prothrombin gene G20210A mutations: a case report.


Bulut O., Ince Z. , Uzunhan O. , Coban A.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, vol.29, no.2, pp.220-222, 2018 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.1097/mbc.0000000000000686
  • Title of Journal : Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
  • Page Numbers: pp.220-222

Abstract

Renal vein thrombosis in a neonate is a rare but well recognized condition with low mortality but high morbidity. The cause has not been explained clearly yet but is probably a multifactorial process that includes inherited prothrombotic abnormalities. Antenatal onset of renal vein thrombosis is important due to the increased risk for permanent organ damage. We report a case of prenatal thrombosis of the renal veins and the inferior vena cava in a newborn with double heterozygosity for factor V Leiden and prothrombin gene mutations who had persistently impaired renal function requiring chronic peritoneal dialysis. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.