Vagus nerve stimulation inhibits seizure activity and protects blood-brain barrier integrity in kindled rats with cortical dysplasia

Kaya M., Orhan N., Karabacak E., Bahceci M. B., Arican N., Ahishali B., ...Daha Fazla

LIFE SCIENCES, cilt.92, ss.289-297, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 92
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.lfs.2013.01.009
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.289-297
  • Anahtar Kelimeler: Cortical dysplasia, Vagus nerve stimulation, Blood-brain barrier, TUBEROUS SCLEROSIS, P-GLYCOPROTEIN, REFRACTORY EPILEPSY, ANIMAL-MODELS, MALFORMATIONS, EPILEPTOGENESIS, EXPRESSION, PHARMACORESISTANCE, NOREPINEPHRINE, HIPPOCAMPUS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aims: This study investigates the effects of vagus nerve stimulation (VNS) on seizure severity and blood-brain barrier (BBB) integrity in kindled rats with cortical dysplasia (CD).