Semilobar holoprosencephaly with associated cyclopia and radial aplasia: first trimester diagnosis by means of integrating 2D-3D ultrasound

Dane B., Dane C., Aksoy F., Yayla M.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.280, no.4, pp.647-651, 2009 (SCI-Expanded) identifier identifier identifier


Holoprosencephaly (HPE) is commonly associated with facial malformations. We present a case of semilobar HPE associated with distal limb defect which was detected at 12 weeks of gestation.