Leptospiral Lymphadenopathy: Case Report


Ekinci O., TURHAN V., HAHOLU A., Polat E., YİĞİT N., BALOĞLU H.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.31, sa.3, ss.744-747, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5336/medsci.2009-13075
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.744-747
  • İstanbul Üniversitesi Adresli: Evet

Özet

Leptospirosis is a zoonotic infectious disease that can involve many organs and it has variable manifestations. In this paper, we describe epitrochlear lymph node involvement as an isolated finding in a case of anicteric leptospirosis, that, to our knowledge, has not been previously reported. The lymph node was excised and light microscopy showed enlarged secondary follicles with prominent germinal centers, some with bizarre shapes along with an increase in high endothelial venules. A Warthin-Starry stain revealed spirochetal organisms which were cork-screw shaped with hooked ends. Serology for leptospira confirmed this bacterium as the etiology of the reactive lymphadenopathy while tests for syphilis and borreliosis were negative.

Leptospirosis is a zoonotic infectious disease that can involve many organs and it has variable manifestations. In this paper, we describe epitrochlear lymph node involvement as an isolated finding in a case of anicteric leptospirosis, that, to our knowledge, has not been previously reported. The lymph node was excised and light microscopy showed enlarged secondary follicles with prominent germinal centers, some with bizarre shapes along with an increase in high endothelial venules. A Warthin-Starry stain revealed spirochetal organisms which were cork-screw shaped with hooked ends. Serology for leptospira confirmed this bacterium as the etiology of the reactive lymphadenopathy while tests for syphilis and borreliosis were negative.