Cerebral Venous Thrombosis in the Mediterranean Area in Adults. Role of Behcet's Disease as an Underlying Cause

Barlas N. , Akman-Demir G., Bahar S. Z.

MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, vol.3, no.1, 2011 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 3 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.4084/mjhid.2011.044


Cerebral venous and dural sinus thrombosis (CVT) is a rare condition with a wide spectrum of clinical presentations. The epidemiology of the disease has evolved considerably during the recent decades with increasing oral contraceptive use in young and middle-aged women. CVT has various causes including genetic and acquired prothrombotic disorders and it usually has a favorable outcome with a low rate of thrombotic recurrence and mortality. Geographical and ethnic variations between populations may result in different distribution of CVT etiologies leading to different pathophysiological mechanisms and clinical presentations. In CVT series reported mostly from the Americas and the western European countries Behcet's disease (BD) is not reported as a common cause of CVT. However it can be discerned as a frequent cause of CVT in BD series. Due to the high prevalence of BD in the southeast Mediterranean region BD is a frequent cause of CVT in the area. Discerning characteristics of patients with BD and CVT have been reported previously and these might be helpful in guiding diagnosis and treatment of CVT especially in this part of the world.