Increased frequency of the S-allele of the L-myc oncogene in breast cancer

ISBIR T., Yaylim I., ARIKAN S., KUCUCUK S., CAMLICA H.

MOLECULAR MEDICINE, vol.8, no.9, pp.521-524, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 9
  • Publication Date: 2002
  • Doi Number: 10.1007/bf03402161
  • Journal Name: MOLECULAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.521-524
  • Istanbul University Affiliated: Yes

Abstract

Background: Association between restriction fragment length polymorphisms (RFLP) of known oncogenes and a predisposition to develop cancer have been postulated. The L-myc gene is a potential molecular marker associated with cancer susceptibility as well as metastasis, prognosis, and adverse survival. Our aim was to test the hypothesis that there was an association between L-myc S allele in breast cancer and a predisposition to the disease.