Increased frequency of the S-allele of the L-myc oncogene in breast cancer
MOLECULAR MEDICINE, cilt.8, sa.9, ss.521-524, 2002 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8 Sayı: 9
- Basım Tarihi: 2002
- Doi Numarası: 10.1007/bf03402161
- Dergi Adı: MOLECULAR MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.521-524
- İstanbul Üniversitesi Adresli: Evet
Özet
Background: Association between restriction fragment length polymorphisms (RFLP) of known oncogenes and a predisposition to develop cancer have been postulated. The L-myc gene is a potential molecular marker associated with cancer susceptibility as well as metastasis, prognosis, and adverse survival. Our aim was to test the hypothesis that there was an association between L-myc S allele in breast cancer and a predisposition to the disease.