Flow Cytometric Evaluation of Pregnancy-Induced Anti-Donor Immunization

Ayna T. K., Ciftci H. S., Tozkir H., Sagiroglu T., Isitmangil G., Gurtekin B., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.44, sa.6, ss.1656-1659, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.transproceed.2012.04.027
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1656-1659
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background. Living donor kidneys from spouses and children (from offspring to parents) are currently considered to be important organ sources. However, pregnancy-induced alloimmunization may provoke acute rejection episodes after kidney transplantation, being flow cytometry cross-match (FCXM) we studied donor-specific antibodies (DSAs) in the sera of recipients planned for living kidney transplantation from their spouse or children. When the FCXM was positive, we confirmed the existence of anti-human leukocyte antigen (H LA) antibodies using flow cytometry panel-reactive antibody (flow-PRA).