Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease


DEMIRKAYA E., Zhou Q., Smith C. K. , Ombrello M. J. , Deuitch N., Tsai W. L. , ...Daha Fazla

ARTHRITIS & RHEUMATOLOGY, cilt.69, ss.1832-1839, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 69 Konu: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/art.40158
  • Dergi Adı: ARTHRITIS & RHEUMATOLOGY
  • Sayfa Sayıları: ss.1832-1839

Özet

Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.