Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease


DEMIRKAYA E., Zhou Q., Smith C. K., Ombrello M. J., Deuitch N., Tsai W. L., ...Daha Fazla

ARTHRITIS & RHEUMATOLOGY, cilt.69, sa.9, ss.1832-1839, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/art.40158
  • Dergi Adı: ARTHRITIS & RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1832-1839
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective. To identify a genetic cause of early-onset systemic lupus erythematosus (SLE) in a large consanguineous family from Turkey and to study the mechanisms of the disease.