IN VITRO ANTITUMOR EFFECTS OF A NEW CULTIVAR (GURARSLAN) OF TRIGONELLA FOENUM GRAECUM L.


AKTAŞ H., Altun S.

AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, cilt.12, sa.3, ss.113-119, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4314/ajtcam.v12i3.14
  • Dergi Adı: AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES
  • Sayfa Sayıları: ss.113-119

Özet

Background: The main goals of our study were as follows: (1) to investigate whether the methanolic extract of the new cultivar (Gurarslam) of Trigonella foenum graecum L. seeds exhibit antiproliferative effects on the HeLa human cervix carcinoma, Mat-LyLu rat prostate carcinoma and 3T3 embryonic mouse fibroblast cell lines, (2) to determine how mitosis and DNA synthesis are affected in cancer cells by the extract, and (3) to observe the changes in cell morphology after treatment with the extract.