Assessment of DNA damage in postmenopausal women under hormone replacement therapy

Ozcagli E., Sardas S., Biri A.

MATURITAS, vol.51, no.3, pp.280-285, 2005 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 51 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1016/j.maturitas.2004.08.010
  • Journal Name: MATURITAS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.280-285
  • Keywords: alkaline comet assay, hormone replacement therapy, postmenopausal women, SISTER-CHROMATID EXCHANGE, BREAST-CANCER RISK, COMET ASSAY, IN-VITRO, TIBOLONE, ESTROGENS, CELLS, GENOTOXICITY, ENDOMETRIAL, FREQUENCIES
  • Istanbul University Affiliated: Yes

Abstract

Objective: To evaluate the possible DNA damage in peripheral blood leukocytes of postmenopausal women under different hormone replacement therapies (HRT), comet assay, a standard method for assessing genotoxicity has been used.