Gender differences in acute stroke: Istanbul Medical School Stroke Registry

Yesilot N., Koyuncu B. A., Coban O., Tuncay R., Bahar S. Z.

NEUROLOGY INDIA, vol.59, no.2, pp.174-179, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.4103/0028-3886.79130
  • Journal Name: NEUROLOGY INDIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.174-179
  • Istanbul University Affiliated: Yes


Background: We aimed to investigate gender differences in Turkish stroke patients. Material and Methods: Demographics, risk factors, clinical and etiologic subtypes, laboratory findings, clinical course, and in-hospital prognosis of 1 522 patients with ischemic stroke (IS) and 320 patients with intracerebral hemorrhage prospectively registered in the Istanbul Medical School Stroke Registry (1994-2004) were analyzed separately. Results: The mean age of IS patients was higher in females (n : 751) (P<0.0001). In males, smoking, ischemic heart disease, peripheral arterial disease, posterior circulation syndromes, and strokes due to large-artery atherosclerosis were more common (P<0.0001 for each). Prestroke disability, atrial fibrillation (P<0.0001), hypertension (P=0.041), modified Rankin Scale (mRS) 3-5 at admission (P<0.0001), total anterior circulation syndrome (P<0.0001), and cardioembolic stroke (P<0.0001) were more frequent in females. Female gender was an independent predictor of poor outcome (mRS 3-6). Conclusion: Gender differences were observed exclusively in patients with IS. Although our patients were younger than those reported, gender differences were similar.