Moxifloxacin activity against clinical isolates compared with the activity of ciprofloxacin


Aktas Z., Gonullu N., Salcioglu M., Bal C., Ang O.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, cilt.20, ss.196-200, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 3
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0924-8579(02)00174-7
  • Dergi Adı: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
  • Sayfa Sayıları: ss.196-200

Özet

The activity of moxifloxacin, a new 8-methoxyquinolone, was compared in vitro with the activity of ciprofloxacin against clinical strains isolated from various sites of infection. The mode MIC values of moxifloxacin were superior to those of ciprofloxacin against Streptococcus pneumoniae, methicillin-susceptible and -resistant Staphylococcus aureus, Enterococcus spp., Escherichia coli and Acinetobacter spp., while ciprofloxacin was more active against Klebsiella pneumoniae and Pseudomonas spp. Both antibiotics had similar activity against Haemophilus influenzae, Moraxella catarrhalis and Enterobacter spp. (C) 2002 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.