Synthetic exploitation of halogenated alkenes containing an electron-withdrawing group: synthesis of alpha-chlorohydrazones and ketene aminals by regiospecific reactions of in situ generated imide chlorides


Tuyun A. F.

TETRAHEDRON LETTERS, cilt.55, sa.13, ss.2085-2089, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Konu: 13
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.tetlet.2014.02.038
  • Dergi Adı: TETRAHEDRON LETTERS
  • Sayfa Sayıları: ss.2085-2089

Özet

A concise approach for the construction of ketene aminals and alpha-chlorohydrazones has been developed. It involves reactions of the regiodefined gem-dihalo nitrovinyl compound of in situ generated imide chlorides in different media with primary arylamines being dependent on the aryl groups. A range of ketene aminals and alpha-chlorohydrazones are obtained in good to high yields. In addition, alpha-aminohydrazones are prepared by using alpha-chlorohydrazones as the precursors. (C) 2014 Elsevier Ltd. All rights reserved.