The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-kappa B signaling


ERDOGAN S., DOĞANLAR O., DOĞANLAR Z. B. , SERTTAŞ R., Turkekul K., DIBIRDIK İ., ...More

LIFE SCIENCES, vol.162, pp.77-86, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 162
  • Publication Date: 2016
  • Doi Number: 10.1016/j.lfs.2016.08.019
  • Title of Journal : LIFE SCIENCES
  • Page Numbers: pp.77-86

Abstract

Aims: Cancer stem cells (CSCs) are involved in drug resistance, metastasis and recurrence of cancers. The efficacy of apigenin on cell survival, apoptosis, migration and stemness properties were analyzed in CSCs.