The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-kappa B signaling


ERDOGAN S., DOĞANLAR O., DOĞANLAR Z. B. , SERTTAŞ R., Turkekul K., DIBIRDIK İ., ...Daha Fazla

LIFE SCIENCES, cilt.162, ss.77-86, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 162
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.lfs.2016.08.019
  • Dergi Adı: LIFE SCIENCES
  • Sayfa Sayıları: ss.77-86

Özet

Aims: Cancer stem cells (CSCs) are involved in drug resistance, metastasis and recurrence of cancers. The efficacy of apigenin on cell survival, apoptosis, migration and stemness properties were analyzed in CSCs.