The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-kappa B signaling

ERDOGAN, SUAT; DOĞANLAR, OGUZHAN; DOĞANLAR, ZEYNEP; SERTTAŞ, RIZA; Turkekul, Kader; DIBIRDIK, İLKER; Bilir, Ayhan

doi:10.1016/j.lfs.2016.08.019

The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-kappa B signaling

ERDOGAN S., DOĞANLAR O., DOĞANLAR Z. B., SERTTAŞ R., Turkekul K., DIBIRDIK İ., ...Daha Fazla

LIFE SCIENCES, cilt.162, ss.77-86, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 162
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.lfs.2016.08.019
Dergi Adı: LIFE SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.77-86
İstanbul Üniversitesi Adresli: Hayır

Özet

Aims: Cancer stem cells (CSCs) are involved in drug resistance, metastasis and recurrence of cancers. The efficacy of apigenin on cell survival, apoptosis, migration and stemness properties were analyzed in CSCs.