Does Hyperbaric Oxygen Administration Before or After Irradiation Decrease Side Effects of Irradiation on Implant Sites?

Tumerdem-Ulug B., Kuran I., Ozden B. C., Mete O., Kemikler G., Aktas Ş., ...More

ANNALS OF PLASTIC SURGERY, vol.67, no.1, pp.62-67, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1097/sap.0b013e3181e6cfa4
  • Journal Name: ANNALS OF PLASTIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.62-67
  • Istanbul University Affiliated: Yes

Abstract

Background: One of the main limitations of implant-based breast reconstruction is the high rate of complications such as capsular contracture and poor aesthetic outcome, due to adjuvant radiotherapy. Hyperbaric oxygen treatment (HBOT) has been used to assist wound healing in the prevention and treatment of the side effects of irradiation. We aimed to investigate this effect of HBOT on the capsule reaction and skin, applied before and after irradiation, following the placement of an implant under the dorsal skin of the rat.