Journal of pharmacology and clinical trials, cilt.1, no.2, ss.70-74, 2019 (Diğer Kurumların Hakemli Dergileri)
Parkinson's disease (PD) is a degenerative process affecting
the basal ganglia, mainly substantia nigra and other brainstem
pigmented neurons, and is manifested by dopamine deficiency
in the brain. The main clinical findings are rest tremor, bradykinesia, rigidity and posterior reflex disorder. Studies indicate
that approximately 1% of the population over 65 years of age
is involved in this disease. Today, the cause of nigral degeneration responsible for the development of this disease is unknown.
However, considering the studies, it can be seen that hereditary
predisposition, environmental toxins and aging play an important role in this process and especially multifactorial causes are
prominent. PD treatment is lifelong and its main treatment is
the substitution of dopamine hormone and reduction of symptoms.
Here, vitamins and herbal supplements that play a role in the
prevention and treatment of Parkinson's are briefly reviewed.