The presence of promatrix metalloproteinase-3 and its relation with different categories of coal workers' pneumoconiosis

Altin R., Kart L., Tekin I. O., Armutcu F., Tor M., Ornek T.

MEDIATORS OF INFLAMMATION, vol.13, no.2, pp.105-109, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.1080/09629350410001688549
  • Journal Name: MEDIATORS OF INFLAMMATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.105-109
  • Istanbul University Affiliated: No

Abstract

Extracellular matrix formation (ECM) and remodeling are critical events related to the pathogenesis of pulmonary fibrosis. Matrix metalloproteinases play an essential role in degrading and remodeling the ECM. In this study, we tried to show the presence and correlation of promatrix metalloproteinase-3 (proMMP-3) ( the inactive form of metalloproteinase-3) levels in coal workers' pneumoconiosis ( CWP) with different categories.