Cardioactive terpenoids and a new rearranged diterpene from Salvia syriaca


ULUBELEN A., OKSUZ S., KOLAK U., Birman H., VOELTER W.

PLANTA MEDICA, vol.66, no.7, pp.627-629, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 7
  • Publication Date: 2000
  • Doi Number: 10.1055/s-2000-8629
  • Journal Name: PLANTA MEDICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.627-629
  • Istanbul University Affiliated: Yes

Abstract

From the roots of Salvia syriaca L., in addition to known terpenoids, a new rearranged diterpene, named salvisyrianone, was isolated. The structure of the new compound was assigned from spectral data, The crude extract and the single compounds were tested for cardiovascular parameters using Wistar Albino rats. Antihypertensive activity was established in the crude extract of the roots as well as in two compounds, ferruginol and 3 beta -hydroxystigmast-5-en-7-one.