Cardioactive terpenoids and a new rearranged diterpene from Salvia syriaca

ULUBELEN A., OKSUZ S., KOLAK U., Birman H., VOELTER W.

PLANTA MEDICA, cilt.66, sa.7, ss.627-629, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 7
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1055/s-2000-8629
  • Dergi Adı: PLANTA MEDICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.627-629
  • İstanbul Üniversitesi Adresli: Evet

Özet

From the roots of Salvia syriaca L., in addition to known terpenoids, a new rearranged diterpene, named salvisyrianone, was isolated. The structure of the new compound was assigned from spectral data, The crude extract and the single compounds were tested for cardiovascular parameters using Wistar Albino rats. Antihypertensive activity was established in the crude extract of the roots as well as in two compounds, ferruginol and 3 beta -hydroxystigmast-5-en-7-one.