A Rare Case of Intraorally Localized Neurofibromatosis Type 1: Case Report


Gürkan Köseoğlu B. , Koltuk M. , Cesur A., Baygın M., Olgaç N. V.

Turkish Association of Oral and Maxillofacial Surgery 26th International Scientific Congress, Girne, Kıbrıs (Kktc), 28 Nisan - 02 Mayıs 2019, ss.187-188

  • Basıldığı Şehir: Girne
  • Basıldığı Ülke: Kıbrıs (Kktc)
  • Sayfa Sayıları: ss.187-188

Özet

Objective: Neural lesions in the oral region are rare. Neurofibroma originating from Schwann cells

and perineuronal fibroblasts is a benign neural tumor. Neurofibromatosis, also known as Von

Recklinghausen disease, is an autosomal dominant disease affecting many organs. Although it

usually shows skin involvement, oral involvement may be seen in 10-25% of patients.

Neurofibromas have a 8-13% risk of malignant transformation.

Case: A 34-year-old female patient with neurofibromatosis type 1 referred the Istanbul University

Department of Oral and Maxillofacial Surgery. There was a lesion at right maxilla between canine

and first premolar for 15 years which was smooth, swelling vestibule, regular border, looks like

lipoma. Panoramic radiograph showed a regular radiolucent lesion. Cone-beam computed

tomography showed a cut-off in the palatinal cortical border. The lesion was enucleated under local

anesthesia. Histopathological examination revealed neurofibroma.

Conclusion: neural lesions may be confused with non-ulcerated tissue proliferation in the oral

region. Correct anamnesis and histopathological examination are important. The patient was

followed-up regularly due to risk of malignant transformation.