Permeable endothelium and the interstitial space of brain

Brightman M., Kaya M.

CELLULAR AND MOLECULAR NEUROBIOLOGY, vol.20, no.2, pp.111-130, 2000 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2000
  • Doi Number: 10.1023/a:1006944203934
  • Journal Name: CELLULAR AND MOLECULAR NEUROBIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-130
  • Istanbul University Affiliated: No

Abstract

1. Fenestrated vessels can be reversibly induced in brain by agents that stimulate urokinase production. This plasminogen activator, like vascular endothelial growth factor and metalloproteinases, is secreted by tumor cells and may account for induction of fenestrated vessels. Why only some of the brain's barrier vessels are converted to fenestrated vessels is unknown.