Chromosomal and microsatellite instability in sporadic gastric cancer

Hiyama, T; Tanaka, S; Yoshihara, M; Sasao, S; Kose, K; Shima, H; Tuncel, H; Ueno, Y; Ito, M; Kitadai, Y; Yasui, W; Haruma, K; Chayama, K

doi:10.1111/j.1440-1746.2004.03369.x

Chromosomal and microsatellite instability in sporadic gastric cancer

Hiyama T., Tanaka S., Yoshihara M., Sasao S., Kose K., Shima H., ...More

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.19, no.7, pp.756-760, 2004 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 19 Issue: 7
Publication Date: 2004
Doi Number: 10.1111/j.1440-1746.2004.03369.x
Journal Name: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.756-760
Istanbul University Affiliated: No

Abstract

Background: Gastric cancer can progress through two pathways of genomic instability: chromosomal (CIN) and microsatellite instability (MSI). It is hypothesized that these two pathways are not always independent and that some tumors show overlap between these two mechanisms.