Chromosomal and microsatellite instability in sporadic gastric cancer

Hiyama T., Tanaka S., Yoshihara M., Sasao S., Kose K., Shima H., ...More

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.19, no.7, pp.756-760, 2004 (SCI-Expanded) identifier identifier identifier


Background: Gastric cancer can progress through two pathways of genomic instability: chromosomal (CIN) and microsatellite instability (MSI). It is hypothesized that these two pathways are not always independent and that some tumors show overlap between these two mechanisms.