Wood pallets are important carrying tools, defined in packaging engineering, for fragile or any kind of heavy goods. Wood pallets are exposed to flexural forces resulting in fracture and fatigue during transportation. In this research, the fracture and fatigue behavior of wood pallet system under loading was investigated, taking into account nail and pallet material behavior, using strain-stress distribution by computational finite element analysis. Static and dynamic numerical analysis was performed on the 3D model of poplar wood pallet using ANSYS computational system. To validate the data gathered from Von Mises yield, Goodman and N-S fatigue diagrams were established to predict fatigue life. The finite element models built in this research may assist the design engineers and manufacturers in evaluation of new design strategies of poplar wood pallets.