HCV-specific lymphocyte responses in individuals with positive anti-HCV but negative HCV-RNA

SİLİ, ULUHAN; Kaya, Abdurrahman; Aydin, Selda; Hondur, Nur; Mert, Ali; Tabak, Ömer; Ozaras, Resat; Ozturk, Recep

doi:10.1016/j.jcv.2015.04.014

HCV-specific lymphocyte responses in individuals with positive anti-HCV but negative HCV-RNA

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SİLİ U., Kaya A., Aydin S., Hondur N., Mert A., Tabak F., ...More

JOURNAL OF CLINICAL VIROLOGY, vol.67, pp.73-77, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 67
Publication Date: 2015
Doi Number: 10.1016/j.jcv.2015.04.014
Journal Name: JOURNAL OF CLINICAL VIROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.73-77
Istanbul University Affiliated: Yes

Abstract

Background: Hepatitis C virus (HCV) status cannot be reliably predicted in anti-HCV positive/HCV-RNA negative individuals who may either have recovered spontaneously or have a false-positive test due to antibody cross-reaction. Investigating T lymphocyte responses in individuals with different HCV status may help understand the cellular immune mechanisms underlying spontaneous recovery, treatment response, and chronicity.