Transcranial direct current stimulation improves seizure control in patients with Rasmussen encephalitis


Tekturk P., Erdogan E. T., Kurt A., Kocagoncu E., Kucuk Z., KINAY D., ...More

EPILEPTIC DISORDERS, vol.18, no.1, pp.58-66, 2016 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1684/epd.2016.0796
  • Journal Name: EPILEPTIC DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.58-66
  • Keywords: direct current stimulation, Rasmussen encephalitis, epilepsy, NONINVASIVE BRAIN-STIMULATION, VAGUS NERVE-STIMULATION, CORTICAL EXCITABILITY, MAGNETIC STIMULATION, REFRACTORY EPILEPSY, HEALTHY-SUBJECTS, DC POLARIZATION, FOCAL EPILEPSY, CLINICAL-TRIAL, MOTOR FUNCTION
  • Istanbul University Affiliated: Yes

Abstract

Aim. Rasmussen encephalitis is associated with severe seizures that are unresponsive to antiepileptic drugs, as well as immunosuppressants. Transcranial direct current stimulation (t-DCS) is a non-invasive and safe method tried mostly for focal epilepsies with different aetiologies. To date, there is only one published study with two case reports describing the effect of t-DCS in Rasmussen encephalitis. Our aim was to investigate the effect of t-DCS on seizures in Rasmussen encephalitis and to clarify its safety.