Clinical, Genetic, and Outcome Characteristics of Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis

Nepesov S., Yaman Y., Elli M., Bayram N., Ozdilli K., Kiykim A., ...More

TURKISH ARCHIVES OF PEDIATRICS, vol.57, no.4, pp.398-405, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.5152/turkarchpediatr.2022.21314
  • Journal Name: TURKISH ARCHIVES OF PEDIATRICS
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.398-405
  • Keywords: Genetic analysis, children, primary hemophagocytic lymphohistiocytosis, NERVOUS-SYSTEM INVOLVEMENT, CNS INVOLVEMENT, CHILDREN, FREQUENCY, ADULTS, HLH
  • Istanbul University Affiliated: Yes

Abstract

ObjectIive: In this study, we sought to describe the clinical, laboratory, and genetic characteristics of patients diagnosed with primary hemophagocytic lymphohistiocytosis. Thus, we aimed to evaluate the early diagnosis and appropriate treatment options for pediatric hemophagocytic lymphohistiocytosis patients.