"‘Conformation Analysis Of Drug-Based Dipeptides’"
Journal of Qafqaz University, vol.23, pp.103-108, 2008 (Peer-Reviewed Journal)
- Publication Type: Article / Article
- Volume: 23
- Publication Date: 2008
- Journal Name: Journal of Qafqaz University
- Page Numbers: pp.103-108
- Istanbul University Affiliated: Yes
Abstract
Conformational properties of the two drug-based dipeptides pGlu-Asn and Pro-Tyr and some of its analogs have been investigated by semiempirical energy calculation method. The optimal conformations of the all dihedral angle values of the backbone and side chains, as well intra- and inter-residue interaction energies were determined. It was shown that the spatial structure of these dipeptides can be described by a set of low-energy conformations.