Effect of Over-the-Counter Topical Agents on Denture-Induced Traumatic Lesions: A Clinical Study

Bural C. , Guven M. C. , Kayacioglu B., Ak G. , Bayraktar G., Bilhan H.

INTERNATIONAL JOURNAL OF PROSTHODONTICS, cilt.31, ss.481-484, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.11607/ijp.5803
  • Sayfa Sayıları: ss.481-484


Purpose: To investigate the effects of over-the-counter products on the healing of denture-induced ulcerations and patients' self-reported pain. Materials and Methods: A total of 140 patients with acute denture-induced ulcerations were randomized into seven treatment groups: denture grinding (control); topical application of corn oil gel (placebo); triester glycerol oxide gel; D-panthenol gel; D-panthenol mouthwash; L-arginine mouthwash; and hyaluronic acid gel. Healing and self-reported pain were assessed after 1, 3, and 7 days of treatment. Results: The percentage of healed lesions in the mandible and maxilla after 7 days was 67% and 65%, respectively. The only significance in healing was for mandibular lesions at 3 days after application of L-arginine mouthwash; at this period, the healing rate was significantly higher than d-panthenol gel, d-panthenol mouthwash, and hyaluronic acid gel (P < .05). Conclusion: Denture grinding as the current protocol for acute denture-induced ulcerations should remain as the default.