Effect of Over-the-Counter Topical Agents on Denture-Induced Traumatic Lesions: A Clinical Study
INTERNATIONAL JOURNAL OF PROSTHODONTICS, vol.31, no.5, pp.481-484, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 31 Issue: 5
- Publication Date: 2018
- Doi Number: 10.11607/ijp.5803
- Journal Name: INTERNATIONAL JOURNAL OF PROSTHODONTICS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.481-484
- Istanbul University Affiliated: Yes
Abstract
Purpose: To investigate the effects of over-the-counter products on the healing of denture-induced ulcerations and patients' self-reported pain. Materials and Methods: A total of 140 patients with acute denture-induced ulcerations were randomized into seven treatment groups: denture grinding (control); topical application of corn oil gel (placebo); triester glycerol oxide gel; D-panthenol gel; D-panthenol mouthwash; L-arginine mouthwash; and hyaluronic acid gel. Healing and self-reported pain were assessed after 1, 3, and 7 days of treatment. Results: The percentage of healed lesions in the mandible and maxilla after 7 days was 67% and 65%, respectively. The only significance in healing was for mandibular lesions at 3 days after application of L-arginine mouthwash; at this period, the healing rate was significantly higher than d-panthenol gel, d-panthenol mouthwash, and hyaluronic acid gel (P < .05). Conclusion: Denture grinding as the current protocol for acute denture-induced ulcerations should remain as the default.