Usefulness of the epithelial tumor marker CA-125 in non-Hodgkin's lymphoma

Ozguroglu, Mustafa; Turna, H; Demir, G; Doventas, Alper; Demirelli, Fuat; Mandel, Nil; Buyukunal, Evin; Serdengecti, S; Berkarda, B

doi:10.1097/00000421-199912000-00014

Usefulness of the epithelial tumor marker CA-125 in non-Hodgkin's lymphoma

Atıf İçin Kopyala

Ozguroglu M., Turna H., Demir G., Doventas A., Demirelli F. H., Mandel N. K., ...Daha Fazla

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, cilt.22, sa.6, ss.615-618, 1999 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 6
Basım Tarihi: 1999
Doi Numarası: 10.1097/00000421-199912000-00014
Dergi Adı: AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.615-618
İstanbul Üniversitesi Adresli: Evet

Özet

CA-125: a commonly used tumor marker for epithelial ovarian cancer, Is a glycoprotein found in normal tissues derived from coelomic epithelia. Increased serum levels of CA-125 have also been found in nongynecologic tumors and nonmalignant diseases involving the peritoneum. A few recent studies and sporadic case reports have reported increased CA-125 levels in patients with non-Hodgkin's lymphoma (NHL). In our study, we aimed to evaluate the serum levels of CA-125 in patients with NHL and determine its potential role to show disease activity in NHL. Serum levels of CA-125 were measured in 61 patients with NHL and were found to be correlated with clinical stage, site of involvement, and disease activity.