Effects of Blood Pressure Lowering With Different Antihypertensive Agents on Cognitive Function and Plasma Brain-derived Neurotrophic Factor Levels: A Comparative Study

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Demir M., Gurol A. O., Ozyigit R. T., Uresin A. Y.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, vol.67, no.6, pp.538-543, 2016 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 67 Issue: 6
• Publication Date: 2016
• Doi Number: 10.1097/fjc.0000000000000377
• Journal Name: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.538-543
• Istanbul University Affiliated: Yes

Abstract

Purpose: Hypertension is a risk factor for cognitive impairment (CI). However, the specific effect of antihypertensive therapy on cognitive function is still controversial. We aimed to investigate the effect of antihypertensive agents targeting the renin-angiotensin system (RAS) on CI and brain-derived neurotropic factor (BDNF).