Decreased prohepcidin levels in patients with HBV-related liver disease: relation with ferritin levels.

Yonal, Oya; Akyuz, Filiz; Demir, Kadir; Ciftci, Sevgi; Keskin, Fahriye; Pinarbasi, Binnur; Uyanikoglu, Ahmet; Issever, Halim; Ozdil, Sadakat; Boztas, Gungor; Besisik, Selman; Kaymakoglu, Sabahattin; Cakaloglu, Yilmaz; Mungan, Zeynel; Okten, Atilla

doi:10.1007/s10620-010-1183-8

Decreased prohepcidin levels in patients with HBV-related liver disease: relation with ferritin levels.

Yonal O., Akyuz F., Demir K., Ciftci S., Keskin F., Pinarbasi B., ...Daha Fazla

Digestive diseases and sciences, cilt.55, sa.12, ss.3548-51, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 55 Sayı: 12
Basım Tarihi: 2010
Doi Numarası: 10.1007/s10620-010-1183-8
Dergi Adı: Digestive diseases and sciences
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3548-51
Anahtar Kelimeler: Prohepcidin, Iron, Hepatitis B, Cirrhosis, CHRONIC HEPATITIS-C, IRON-METABOLISM, HEPCIDIN EXPRESSION, INFLAMMATION, CIRRHOSIS
İstanbul Üniversitesi Adresli: Evet

Özet

Levels of prohepcidin, a homeostatic regulator of iron absorption, are altered in chronic hepatitis C and liver cirrhosis. However, data on the potential alterations of prohepcidin in patients with HBV-related liver disease are scarce. We investigated whether serum prohepcidin is related to iron overload and perenchymal dysfuction in HBV-related liver disease.