Partial load-bearing rabbit ulnar segmental defects are regenerated with biocompatible grafts with or without bone marrow-derived mesenchymal stem cells

Basaran S. H., Bayrak A., TANRIVERDİ G., Tanriverdi B., Avkan M. C.

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.28, sa.8, ss.1066-1072, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.14744/tjtes.2021.64569
  • Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1066-1072
  • Anahtar Kelimeler: Bone regeneration, bone scaffold, bone tissue engineering, mesenchymal stem cells, rabbit, segmental bone defect, MORPHOGENETIC PROTEIN-2, STROMAL CELLS, REPAIR, RECONSTRUCTION, COMPOSITE, SCAFFOLDS, ENHANCEMENT, SULFATE, SITE
  • İstanbul Üniversitesi Adresli: Hayır

Özet

BACKGROUND: The autologous bone grafts still have been used as the gold standard to initiate and facilitate bone healing in cases with bone defects. Because of some disadvantages of autologous bone grafts, the new biocomposite grafts have been researched. The purpose of the present study was to investigate whether the bone marrow-derived mesenchymal stem cells (BM-MSCs) loaded into a biocomposite scaffold enhance bone regeneration.