Partial load-bearing rabbit ulnar segmental defects are regenerated with biocompatible grafts with or without bone marrow-derived mesenchymal stem cells

Basaran S. H., Bayrak A., TANRIVERDİ G., Tanriverdi B., Avkan M. C.

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.28, no.8, pp.1066-1072, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 8
  • Publication Date: 2022
  • Doi Number: 10.14744/tjtes.2021.64569
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1066-1072
  • Keywords: Bone regeneration, bone scaffold, bone tissue engineering, mesenchymal stem cells, rabbit, segmental bone defect, MORPHOGENETIC PROTEIN-2, STROMAL CELLS, REPAIR, RECONSTRUCTION, COMPOSITE, SCAFFOLDS, ENHANCEMENT, SULFATE, SITE
  • Istanbul University Affiliated: No

Abstract

BACKGROUND: The autologous bone grafts still have been used as the gold standard to initiate and facilitate bone healing in cases with bone defects. Because of some disadvantages of autologous bone grafts, the new biocomposite grafts have been researched. The purpose of the present study was to investigate whether the bone marrow-derived mesenchymal stem cells (BM-MSCs) loaded into a biocomposite scaffold enhance bone regeneration.