The effects of vanadyl sulfate on glutathione, lipid peroxidation and nonenzymatic glycosylation levels in various tissues in experimental diabetes

TUNALI S., YANARDAĞ R.

ISTANBUL JOURNAL OF PHARMACY, vol.51, no.1, pp.73-78, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.26650/istanbuljpharm.2020.0107
  • Title of Journal : ISTANBUL JOURNAL OF PHARMACY
  • Page Numbers: pp.73-78

Abstract

Background and Aims: Diabetes mellitus is characterized by hyperglycemia which over time leads to serious damage of several body systems. Vanadium ions and their complexes have been demonstrated to have various insulin-mimetic and antidiabetic effects. The object of the present work was to investigate the effect of vanadyl sulfate ( VS) on serum total lipid and protein parameters, glutathione, lipid peroxidation and nonenzymatic glycosylation levels in cardiac, lens, lung and skeletal muscle tissues of STZ diabetic rats.