The role of laparoscopic sleeve gastrectomy on inflammatory parameters n morbidly obese patients

Ergun S., Ergun D. D., Akinci O., TAŞKIN H. E., ŞİMŞEK G., Taskin M., ...More

JOURNAL OF VISCERAL SURGERY, vol.159, no.1, pp.31-38, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 159 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.1016/j.jviscsurg.2020.11.009
  • Journal Name: JOURNAL OF VISCERAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.31-38
  • Keywords: Morbidly obese patients, Laparoscopic sleeve gastrectomy, Zinc, Zinc alpha-2 glycoprotein, Peroxisome proliferator-activated receptor-gamma, Nuclear factor kappa-B, Y GASTRIC BYPASS, ACTIVATED-RECEPTOR-GAMMA, ADIPOSE-TISSUE, ZINC, EXPRESSION, INSULIN, SURGERY, STRESS, WOMEN
  • Istanbul University Affiliated: Yes

Abstract

Background: Obesity is an excessive increase in body fat mass and triggers chronic inflammation which causes increased fat accumulation in the visceral fat tissue. The aim of this study was to analyze serum zinc (Zn), Zn-alpha 2 glycoprotein (ZAG), peroxisome proliferator-activated receptorni (PPAR-y) and nuclear factor kappa-light-chain-enhancer of activated B cell (NF-KB) levels in morbidly obese patients before and after laparoscopic sleeve gastrectomy (LSG) and determine the association between alteration in body mass index (BMI), the % Excess Weight Loss (% EWL) and the biochemical parameters.